Dr. Deb's Alzheimer's Formula
Top 10 Health Tips | My Health Formulas
The following herbs and nutrients have shown promise in the laboratory as potent reducers of amyloid pathology (the hallmark of AD):
- Curcumin and rosemary are common kitchen herbs that have the strongest effect.
- Supplementing with CoQ10 (an enzyme which decreases with age) has shown a more modest effect.
- Walnut extract inhibits the fibrillization of amyloid beta protein, and also defibrillizes already formed fibrils.
- Ginseng and ashwagandha are herbs that have shown reversal of beta amyloid in mouse brains, as well as regeneration of neurite extensions in damaged cortical neurons.
Accumulations of iron, zinc and copper have been found in beta amyloid aggregations. Chelators for these minerals could therefore prove helpful. Garlic, cilantro, and vitamin C are natural chelators.
Resveratrol (found in red wine) promotes clearance of amyloid-beta peptides.
Ginkgo biloba is perhaps the most widely researched herb in conjunction with AD and other dementias. It appears to work through several mechanisms, including scavenging of free radicals, increasing blood flow to the brain, and blocking events induced by beta-amyloid toxicity. Studies have found improved memory after six months of daily supplementation of 120 mg taken once in the morning.
SAMe (S-adenosyl methionine) is an amino acid derivative which is found in very low concentrations in the brains of people who have AD. Low levels of SAMe results in loss of control of gene expression in amyloid-beta processing. Supplementing with 400 mg to 800 mg daily can increase the amount of SAMe in the brain.
Folate and vitamin B12 tend to be found in low levels among the elderly. Supplementing these important vitamins is important in reducing levels of homocysteine. High levels of homocysteine in the blood has been strongly related to development and severity of AD.
Some studies have shown green tea extract to be helpful.
* Note: the formula I've been using with my mother in law which has resulted in modest improvement over two years includes SAMe, ginkgo biloba, green tea extract, and a multivitamin.
Note: My nutritional formulas should be applied in collaboration with your health care provider following a complete assessment by a nutritional consultant to avoid possible drug-herb-food interactions and to address any nutritional imbalances that are unique to you.